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Title   A Clinicopathological Analysis of Recurrent Gastric Cancer
Publicationinfo   2001 Jan; 033(03): 207-216.
Key_word   Stomach neoplasm , Recurrence , Recurrence pattern , Survival
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Abstract   Purpose: This study was designed to investigate the correlation between the clinicopatho logic characteristics and the recurrence pattern of gastric cancerand to defines urvival difference according to treatment modality after diagnosis of recurrence. Materials and Methods : We retrospectively reviewed the medical records of 4184 patients who had undergone radical surgery for primary gastric cancer from 1986 through 1996. Clinicopatho logic factors were analyzedfor the relationship of each factor with the pattern of recurrence. And the survival after diagnosis of recurrence was compared among the treatment modalities. Results: Recurrence pattern was confirmed in 1141 patients. Loco-regional recurrence occurred in 291 patients (20.1%), peritoneal recurrence in 383 (26.5%), distant recurrence in 290 (20.1%), and mixed recurrence in 177 (12.3%), respectively. Early recurrence (less than 2 years ) occurred in 767 (69.3%), intermediate recurrence (2∼5 years ) in 286 (25.8%), and late recurrence (more than 5 years ) in 54 (4.9%). In multivariate analysis, T stage, N stage, size of tumor and perine ural invasion were independent prognostic factors for recurrence. Median survivalfrom diagnosis of recurrence was 24.2 months in the curative operationgroup, 7.7 months in the chemotherapy group, 7.1 months in the non-curative operationgroup and 3.3 months in the conservative treatment group, respectively (p=0.000). Conclusion: The clinic opathological analysis of recurrent gastric cancer showed recurrent patterns and prognostic factors. Curative resection is suggested to have survival benefit in recurrent gastric cancer patients, although it was possible in patients with limited extent of disease. (Cancer Research and Treatment 2001;33:207 - 215)
저 자   양한광(Han Kwang Yang),조삼제(Sam Je Cho),정기욱(Ki Wook Chung),김윤호(Yoon Ho Kim),이현국(Hyeon Kook Lee),이건욱(Kuhn Uk Lee),최국진(Kuk Jin Choe),김진복(Jin Pok Kim)