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Title   위암에서 혈청 및 복강세척액의 CEA , CA19 - 9 치가 예후에 미치는 영향 ( Prognostic Value of CEA and CA19 - 9 in Serum and Peritoneal Washing Fluid in Gastric Carcinoma )
Publicationinfo   1998 Jan; 030(05): 869-879.
Key_word   CEA, CA19-9, Washing cytology, Gastric carcinoma
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Abstract   Purpose: The clinical significance of preoperative serum levels of CEA and CA19-9, levels of CEA and CA19-9 in peritoneal washing fluid and free cancer cells in peritoneal washing fluid in gastric cancer patients were evaluated in this study. Materials and Methods: Serum and peritoneal levels of CEA and CA19-9 and peritoneal washing cytology in 115 patients with gastric cancer were analyzed with respect to the prognostic factors using univariate and multivariate analysis. Results: Positive rate of serum CEA and CA19-9 was 16.5%, 13.0%. And that of peritoneal washing CEA, CA19-9 and cytology was 15.7%, 7.8% and 9.6%. A univariate analysis showed that tumor markets in serum and peritoneal washing fluid and peritoneal washing cytology had significant correlations with the progression of the tumors, and patients with positive serum or peritoneal tumor markers had poorer survival after operation than did the patients with negative tumor markers. But in a multivariate analysis showed that only peritoneal CA19-9 was an independent risk factor. And combination of these five markers provided rnore predictable prognostic informations in a multivariate analysis. Conclusian: Combination of serum or peritoneal levels of CEA, CA19-9 and washing cytology appeared to be a useful marker for managing gastric cancer patients.
저 자   한상욱(Sang Uk Han),조용관(Yong Kwan Cho),홍성우(Seong Woo Hong),임영애(Young Ae Lim),곽연식(Yun Sik Kwak)김명욱(Myung Wook Kim)