논문검색
Author Woo Kyun Bae, M.D.1Hyun Jeong Shim, M.D.1Yoo Duk Choi, M.D.2Jin Woong Kim, M.D.3Sang Hee Cho, M.D.1Ho Cheol Kang, M.D.1Ik Joo Chung, M.D.1
Place of duty Departments of 1Internal Medicine,2Pathology, and 3Radiology, ChonnamNational University Medical School,Gwangju, Korea
Title Severe Hypothyroidism Induced by Thyroid Metastasisof Cholangiocarcinoma
Publicationinfo Cancer Res Treat 2009 Mar; 041(01): 56-57.
Key_word Cholangiocarcinoma, Thyroid metastasis, Hypothyroidism
Full-Text
Abstract We report a case of severe hypothyroidism in a cholangiocarcinoma patient withmetastasis to the thyroid gland. A 58-year-old man was admitted for upper abdominaldiscomfort and multiple palpable neck nodules. Abdominal computed tomography (CT)demonstrated the presence of a 4.7-cm tumor in the right hepatic lobe, and core needlebiopsy revealed it to be cholangiocarcinoma. Neck CT showed a diffuse, low attenuationthyroid gland, and fine-needle aspiration (FNA) demonstrated metastatic adenocarcinoma.Thyroid function tests were initially normal, but the size of the thyroid gland decreased andsevere hypothyroidism developed after chemotherapy was implemented forcholangiocarcinoma. In a patient with malignant disease and a goiter, the possibility of ametastatic tumor involving the thyroid should be seriously considered. Metastatic thyroidcancer and thyroid dysfunction are probably infrequent, but diagnosis is important in theinstitution of appropriate therapy.
출판정보 대한암학회지 2009 Mar; 041(01): 56-57.