논문검색
Author Bokyung Kim, M.D.1, Sung Yong Oh, M.D.1, Suee Lee, M.D.1, Hyuk-Chan Kwon, M.D.1, Sung-Hyun Kim, M.D.1, Sook Hee Hong, M.D.2, Sung-Soo Kim, M.D.3 and Hyo-Jin Kim, M.D.1
Place of duty Departments of 1Internal Medicine, 2Pathology, 3Orthopedic Surgery, Dong-A University College of Medicine, Busan, Korea
Title Unusual Presentation of Large B Cell Lymphoma- Bone and Stomach- Treated with Autologous Transplantation
Publicationinfo Cancer Res Treat 2007 Dec; 039(04): 181-184.
Key_word Extranodal, Diffuse large B-cell lymphoma, Stomach, Bone
Full-Text
Abstract Extranodal presentation of diffuse large B cell lymphoma (DLBL) is frequently observed in the gastrointestinal tract, CNS, bone, testes and liver. However, the simultaneous detection of multiple extranodal involvement at presentation is quite an uncommon occurrence. In this study, we report on a patient with an uncommon presentation of DLBL, and he had symptoms of left knee joint pain and hematemesis, characterized by bone and stomach involvement. Computed tomography and fluorodeoxyglucose-positron emission tomography (FDG-PET) scanning revealed a rapid, extensive spread to the bones and soft tissues. Subsequent histopathological examination verified the bony and gastric CD20-positive DLBL locali-zation. We diagnosed this case as DLBL of stage IV with an international prognostic index of 3, and classified him into the high intermediate risk group. This patient was treated via chemotherapy with an R-CHOP regimen. After achieving a partial response, the patient received autologous peripheral blood stem cell transplantation. The patient attained partial remission, as shown on the FDG-PET scan, and he displayed improvement of his left femur pain. (Cancer Res Treat. 2007;39:181-184)
출판정보 대한암학회지 2007 Dec; 039(04): 181-184.